EVALUATION OF PIPER BETLE L. EXTRACTS AND ITS ANTIVIRULENCE ACTIVITY TOWARDS P. AERUGINOSA
نویسندگان
چکیده
The virulence factor of bacteria such as P. aeruginosa causes severe problems affecting human health and environmental quality. In this study, Piper betle undergoes an extraction process yielding extract to diminish the aeruginosa. efficiency treatment on was measured using Pyoverdine assay. different factors affected yield leaves a solvent ratio (1:6 1:10), method (maceration sonication) solvents (methanol, ethanol, ethyl acetate hexane) were tested. assay illustrates exhibits lowest peak (OD630 = 0.2320) compared methanol, ethanol hexane due presence bioactive compound reducing factor. 1:10 has higher 4.53±0.05 g 1:6 yields 2.86±0.05 extracts because better contact area. Maceration with agitation indicated highest 0.5210±0.05 followed by maceration without at 0.2660±0.05 0.2792±0.05 for sonication. showed is 0.4741±0.05 2.4975±0.05 g, 3.7658±0.05 methanol 6.3331±0.05 polarity. This study aims provide insightful knowledge applied ability antivirulence antibacterial agent against
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ژورنال
عنوان ژورنال: Jurnal teknologi
سال: 2022
ISSN: ['2460-0288']
DOI: https://doi.org/10.11113/jurnalteknologi.v85.18892